Non-Targeted Analytical Technology in Herbal Medicines: Applications, Challenges, and Perspectives
文献类型： 外文期刊
作者： Li, Chaoping 1 ; Wang, Yuanzhong 1 ;
作者机构： 1.Yunnan Acad Agr Sci, Med Plants Res Inst, Kunming, Peoples R China
2.Yunnan Univ Chinese Med, Coll Tradit Chinese Med, Kunming, Peoples R China
3.Yunnan Acad Agr Sci, Med Plants Res Inst, Kunming 650200, Peoples R China
关键词： Applications; chemometrics; herbal medicines (HMs); non-targeted analytical technology
期刊名称：CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY （ 影响因子：5.686； 五年影响因子：6.279 ）
ISSN： 1040-8347
年卷期：
页码：
收录情况： SCI
摘要： Herbal medicines (HMs) have been utilized to prevent and treat human ailments for thousands of years. Especially, HMs have recently played a crucial role in the treatment of COVID-19 in China. However, HMs are susceptible to various factors during harvesting, processing, and marketing, affecting their clinical efficacy. Therefore, it is necessary to conclude a rapid and effective method to study HMs so that they can be used in the clinical setting with maximum medicinal value. Non-targeted analytical technology is a reliable analytical method for studying HMs because of its unique advantages in analyzing unknown components. Based on the extensive literature, the paper summarizes the benefits, limitations, and applicability of non-targeted analytical technology. Moreover, the article describes the application of non-targeted analytical technology in HMs from four aspects: structure analysis, authentication, real-time monitoring, and quality assessment. Finally, the review has prospected the development trend and challenges of non-targeted analytical technology. It can assist HMs industry researchers and engineers select non-targeted analytical technology to analyze HMs' quality and authenticity.
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