文献类型： 外文期刊
作者： Liao, Rongqiang 1 ; Liu, Ying 1 ; Lv, Pin 2 ; Wu, Di 1 ; Xu, Meiling 1 ; Zheng, Xiaoyuan 1 ;
作者机构： 1.Chongqing Univ, Cent Hosp, Chongqing Emergency Med Ctr, Pharm Dept, Chongqing, Peoples R China
2.Yunnan Acad Agr Sci, Ind Crop Res Inst, Kunming, Yunnan, Peoples R China
3.Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kunming, Yunnan, Peoples R China
关键词： Cyclodextrin; poly(ε -lysine); drug carrier; scutellarin
期刊名称：DRUG DELIVERY （ 影响因子：6.419； 五年影响因子：6.169 ）
ISSN： 1071-7544
年卷期： 2020 年 27 卷 1 期
页码：
收录情况： SCI
摘要： A novel beta-cyclodextrin pendant polymer (epsilon-PL-CD), composed of poly(epsilon-lysine) (epsilon-PL) main chain and glycine-beta-cyclodextrin (Gly-CD) side chains, was prepared by a simple two-step procedure. The epsilon-PL-CD was investigated as a drug carrier of hydrophobic drug scutellarin (SCU). The characterization and complexation mode of the SCU:epsilon-PL-CD were researched in both solution and solid state by means of photoluminescence spectroscopy, H-1 and 2D NMR, X-Ray powder diffraction (XRPD), thermal gravimetric analysis, Particle size and Zeta potential. The solubility test indicated that the solubilizing ability of SCU:epsilon-PL-CD was significantly improved compared with SCU:beta-CD and free SCU. Besides, in vitro cell experiment, it was found that SCU:epsilon-PL-CD has a strong inhibitory effect on the growth and invasion of tumor cells. The present study provides useful information for epsilon-PL-CD as a drug carrier material.
- 相关文献
作者其他论文 更多>>
-
Micro-CT data of complete metamorphosis process in Harmonia axyridis
作者：Shu, Runguo;Xiao, Yiqi;Zhang, Chaowei;Zhou, Hang;Li, Fei;Shu, Runguo;Xiao, Yiqi;Zhang, Chaowei;Zhou, Hang;Li, Fei;Liu, Ying
关键词：
-
A chromosome-scale genome assembly of the nipa palm hispid beetle Octodonta nipae
作者：Tang, Baozhen;Fu, Lang;Hou, Youming;Tang, Baozhen;Fu, Lang;Hou, Youming;Tang, Baozhen;Fu, Lang;Hou, Youming;Yin, Chuanlin;Tao, Shaomin;He, Kang;Li, Fei;He, Kang;Li, Fei;He, Kang;Li, Fei;Liu, Ying;Fu, Lang
关键词：
-
A chromosome-level genome assembly of tomato pinworm, Tuta absoluta
作者：Liu, Ying;Yin, Yanqiong;Zhao, Xueqing;Li, Xiangyong;Luo, Xiyan;Gebretsadik, Kifle Gebreegziabiher;Chen, Aidong;Chen, Xi;He, Kang;Mei, Yang;Wang, Zuoqi;Shu, Runguo;Cheng, Ziqi;Li, Fei;Chen, Xi;He, Kang;Mei, Yang;Wang, Zuoqi;Shu, Runguo;Cheng, Ziqi;Li, Fei;Chen, Xi;He, Kang;Mei, Yang;Wang, Zuoqi;Shu, Runguo;Cheng, Ziqi;Li, Fei;Li, Xiaowei;Lv, Yaobin;Gebretsadik, Kifle Gebreegziabiher;Luo, Chen;Wang, Ran
关键词：
-
Red imported fire ant nesting affects the structure of soil microbial community
作者：Song, Jingjie;Zhao, Xueqing;Yin, Yanqiong;Li, Xiangyong;Chen, Fushou;Chen, Aidong;Liu, Ying;Tang, Zhenzhen
关键词：RIFA; soil microbial community (SMC); 16S rDNA; invasion; ecosystem function
-
Population Growth of Fall Armyworm, Spodoptera frugiperda Fed on Cereal and Pulse Host Plants Cultivated in Yunnan Province, China
作者：Gebretsadik, Kifle Gebreegziabiher;Liu, Ying;Yin, Yanqiong;Zhao, Xueqing;Li, Xiangyong;Chen, Fushou;Chen, Aidong;Gebretsadik, Kifle Gebreegziabiher;Zhang, Yong;Chen, Julian
关键词：Spodoptera frugiperda; host plants; life table; survival rate; maize; wheat; barley; faba beans; soya beans
-
Whole-genome resequencing of wild and cultivated cannabis reveals the genetic structure and adaptive selection of important traits
作者：Chen, Xuan;Guo, Hong-Yan;Zhang, Qing-Ying;Guo, Rong;Lv, Pin;Xu, Yan-Ping;Guo, Meng-Bi;Zhang, Yuan;Zhang, Kun;Yang, Ming;Wang, Lu;Zhan, Yi-Xun;Liu, Yan-Hu
关键词：Cannabis; Wild; Cultivated; Whole-genome resequencing; Genetic structure; Flowering
-
Preparation of poly(e-lysine)-cyclodextrin coated Fe3O4 nanoparticles for selective separation of natural medicine: Scutellarin
作者：Liao, Rongqiang;Jiang, Dexi;Liu, Ying;Lv, Pin;Lv, Pin
关键词：Cyclodextrin; Nanoparticles; Separation; Scutellarin
