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Molecular Mechanism and Health Role of Functional Ingredients in Blueberry for Chronic Disease in Human Beings

文献类型： 外文期刊

作者： Ma, Luyao 1 ; Sun, Zhenghai 1 ; Zeng, Yawen 3 ; Luo, Mingcan 2 ; Yang, Jiazhen 3 ;

作者机构： 1.Southwest Forestry Univ, Econ & Management Coll, Kunming 650224, Yunnan, Peoples R China

2.Southwest Forestry Univ, Key Lab Forest Resources Conservat & Utilisat Sou, Minist Educ, Kunming 650224, Yunnan, Peoples R China

3.Yunnan Acad Agr Sci, Biotechnol & Germplasm Resources Inst, Kunming 650205, Yunnan, Peoples R China

关键词： blueberry; functional ingredients; chronic disease; functional food

期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：5.923； 五年影响因子：6.132 ）

ISSN： 1422-0067

年卷期： 2018 年 19 卷 9 期

页码：

收录情况： SCI

摘要： Functional ingredients in blueberry have the best health benefits. To obtain a better understanding of the health role of blueberry in chronic disease, we conducted systematic preventive strategies for functional ingredients in blueberry, based on comprehensive databases, especially PubMed, ISI Web of Science, and CNKI for the period 2008-2018. Blueberry is rich in flavonoids (mainly anthocyanidins), polyphenols (procyanidin), phenolic acids, pyruvic acid, chlorogenic acid, and others, which have anticancer, anti-obesity, prevent degenerative diseases, anti-inflammation, protective properties for vision and liver, prevent heart diseases, antidiabetes, improve brain function, protective lung properties, strong bones, enhance immunity, prevent cardiovascular diseases, and improve cognitive decline. The anthocyanins and polyphenols in blueberry are major functional ingredients for preventive chronic disease. These results support findings that blueberry may be one of the best functional fruits, and further reveals the mechanisms of anthocyanins and polyphenols in the health role of blueberry for chronic disease. This paper may be used as scientific evidence for developing functional foods, nutraceuticals, and novel drugs of blueberry for preventive chronic diseases.

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