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Ethnobotany, Phytochemistry and Pharmacological Properties of Eucommia ulmoides: A Review

文献类型: 外文期刊

作者: Wang, Chao-Yong 1 ; Tang, Li 1 ; He, Jian-Wu 1 ; Li, Jing 1 ; Wang, Yuan-Zhong 1 ;

作者机构: 1.Jishou Univ, Coll Hunan Prov, Natl & Local United Engn Lab Integrat Utilizat Te, Jishou 416000, Peoples R China

2.Jishou Univ, Coll Hunan Prov, Coll Biol Resources & Environm Sci, Jishou 416000, Peoples R China

3.Jishou Univ, Coll Hunan Prov, Key Lab Plant Resources Conservat & Utilizat, Jishou 416000, Peoples R China

4.Yunnan Acad Agr Sci, Inst Med Plants, 2238 Beijing Rd, Kunming 650200, Yunnan, Peoples R China

5.Hunan Appl Technol Univ, Coll A&F Sci & Technol, Changde 415000, Peoples R China

关键词: Eucommia ulmoides; Medicinal History; Botany; Ethnopharmacology; Phytochemistry; Pharmacology; Review

期刊名称:AMERICAN JOURNAL OF CHINESE MEDICINE ( 影响因子:4.667; 五年影响因子:4.135 )

ISSN: 0192-415X

年卷期: 2019 年 47 卷 2 期

页码:

收录情况: SCI

摘要: Eucommia ulmoides Oliver, a single species of Eucommia genus belonging to the Eucommiaceae family, is an endemic in China and has been used in traditional Chinese medicine for nearly two thousand years. Records from different historical periods highlight E. ulmoides and its officinal botanical parts, usefulness in adaptation to disease and its central role in Chinese medicine theory. There are also historical collection documents for minorities in China. Tearing the leaves, bark and fruit produces strands of latex; a description of E. ulmoides's morphological features is recorded in this paper. This review summarizes 204 natural compounds isolated from this plant, which are divided into seven categories: lignans, iridoids, flavonoids, phenols, steroids, terpenes and others. These components possess wide-ranging pharmacological efficacies, such as antihypertensive, antihyperglycemic, antihyperlipidemia, anti-oxidative, anti-osteoporosis, antitumor, immunomodulatory and neuroprotective activities. This review aims to provide a reference for extensive researches of E. ulmoides crude drugs, especially for quality control, biosynthesis and structure modification of active ingredients and pharmacological mechanism.

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