Authentication of Herbal Medicines Based on Modern Analytical Technology Combined with Chemometrics Approach: A Review
文献类型： 外文期刊
作者： Liu, Chunlu 1 ; Zuo, Zhitian 1 ; Xu, Furong 2 ; Wang, Yuanzhong 1 ;
作者机构： 1.Yunnan Acad Agr Sci, Med Plants Res Inst, Kunming 650223, Yunnan, Peoples R China
2.Yunnan Univ Chinese Med, Coll Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China
关键词： Authentication; chemometrics methods; herbal medicines (HMs); modern analytical technology
期刊名称：CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY （ 影响因子：5.686； 五年影响因子：6.279 ）
ISSN： 1040-8347
年卷期：
页码：
收录情况： SCI
摘要： Since ancient times, herbal medicines (HMs) have been widely popular with consumers as a "natural" drug for health care and disease treatment. With the emergence of problems, such as increasing demand for HMs and shortage of resources, it often occurs the phenomenon of shoddy exceed and mixing the false with the genuine in the market. There is an urgent need to evaluate the quality of HMs to ensure their important role in health care and disease treatment, and to reduce the possibility of threat to human health. Modern analytical technology is can be analyzed for analyzing chemical components of HMs or their preparations. Reflecting complex chemical components' characteristic curves in the analysis sample, and the comprehensive effect of active ingredients of HMs. In this review, modern analytical technology (chromatography, spectroscopy, mass spectrometry), chemometrics methods (unsupervised, supervised) and their advantages, disadvantages, and applicability were introduced and summarized. In addition, the authentication application of modern analytical technology combined with chemometrics methods in four aspects, including origin, processing methods, cultivation methods, and adulteration of HMs have also been discussed and illustrated by a few typical studies. This article offers a general workflow of analytical methods that have been applied for HMs authentication and explains that the accuracy of authentication in favor of the quality assurance of HMs. It was provided reference value for the development and application of modern HMs.
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