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Actional Mechanisms of Active Ingredients in Functional Food Adlay for Human Health

文献类型： 外文期刊

作者： Zeng, Yawen 1 ; Yang, Jiazhen 2 ; Chen, Jia 1 ; Pu, Xiaoying 1 ; Li, Xia 1 ; Yang, Xiaomeng 1 ; Yang, Li'e 1 ; Ding, Yumei 1 ; Nong, Mingying 3 ; Zhang, Shibao 3 ; He, Jinbao 3 ;

作者机构： 1.Yunnan Acad Agr Sci, Biotechnol & Germplasm Resources Inst, Agr Biotechnol Key Lab Yunnan Prov, Kunming 650205, Yunnan, Peoples R China

2.Minist Agr, Key Lab Southwestern Crop Gene Resources & Germpl, Kunming 650205, Yunnan, Peoples R China

3.Wenshan Acad Agr Sci, Wenshan 663099, Peoples R China

关键词： adlay; medicine and food homologous; functional ingredient; anti-cancer; anti-obesity; anti-inflammatory; anti-diabetic; anti-oxidant; actional mechanisms

期刊名称：MOLECULES （ 影响因子：4.927； 五年影响因子：5.11 ）

ISSN：

年卷期： 2022 年 27 卷 15 期

页码：

收录情况： SCI

摘要： Medicinal and food homologous adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) plays an important role in natural products promoting human health. We demonstrated the systematic actional mechanism of functional ingredients in adlay to promote human health, based on the PubMed, CNKI, Google, and ISI Web of Science databases from 1988 to 2022. Adlay and its extracts are rich in 30 ingredients with more than 20 health effects based on human and animal or cell cultures: they are anti-cancer, anti-inflammation, anti-obesity, liver protective, anti-virus, gastroprotective, cardiovascular protective, anti-hypertension, heart disease preventive, melanogenesis inhibiting, anti-allergy, endocrine regulating, anti-diabetes, anti-cachexia, osteoporosis preventive, analgesic, neuroprotecting, suitable for the treatment of gout arthritis, life extending, anti-fungi, and detoxifying effects. Function components with anti-oxidants are rich in adlay. These results support the notion that adlay seeds may be one of the best functional foods and further reveal the action mechanism of six major functional ingredients (oils, polysaccharides, phenols, phytosterols, coixol, and resistant starch) for combating diseases. This review paper not only reveals the action mechanisms of adding adlay to the diet to overcome 17 human diseases, but also provides a scientific basis for the development of functional foods and drugs for the treatment of human diseases.

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