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Two new steroids with NO inhibitory effects from lansium domesticum

文献类型: 外文期刊

作者: Ji, Kai-Long 1 ; Dai, Meng-Yuan 2 ; Xiao, Chun-Fen 1 ; Xu, You-Kai 1 ;

作者机构: 1.Chinese Acad Sci, Key Lab Trop Plant Resources & Sustainable Use, Xishuangbanna Trop Bot Garden, Menglun, Peoples R China

2.Yunnan Acad Agr Sci, Ind Crop Res Inst, Kunming, Yunnan, Peoples R China

关键词: Lansium domesticum; steroids; NO inhibition; Meliaceae

期刊名称:NATURAL PRODUCT RESEARCH ( 影响因子:2.158; 五年影响因子:1.885 )

ISSN: 1478-6419

年卷期: 2021 年 35 卷 7 期

页码:

收录情况: SCI

摘要: Chemical investigation of Lansium domesticum has led to the isolation of two undescribed compounds, namely 17(20)E-dyscusin B (1) and 17(20)Z-dyscusin B (2), as well as three known ones (3 - 5). Structural elucidation was accomplished by the analysis of NMR, MS and IR data. Compounds 1 and 2 were a pair of Delta(17(20)) geometric isomers of pregnane steroids and showed the significant nitric oxide (NO) inhibitory activities.

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