文献类型： 外文期刊
作者： Wang, Zhi-Wei 1 ; Li, Yun 1 ; Liu, Da-Hui 3 ; Mu, Yan 1 ; Dong, Hong-Jing 1 ; Zhou, Hong-Lei 2 ; Guo, Lan-Ping 1 ; Wang, 1 ;
作者机构： 1.Qilu Univ Technol, Shandong Acad Sci, Shandong Anal & Test Ctr, Shandong Key Lab TCM Qual Control Technol, Jinan, Shandong, Peoples R China
2.Shandong Univ Tradit Chinese Med, Coll Pharm, Jinan, Shandong, Peoples R China
3.Yunnan Acad Agr Sci, Inst Med Plants, Kunming, Yunnan, Peoples R China
关键词： Phenolics; Gastrodia elata Blume; neuroprotective effects; N-6-(4-hydroxybenzyl) adenosine; grossamide
期刊名称：NATURAL PRODUCT RESEARCH （ 影响因子：2.861； 五年影响因子：2.572 ）
ISSN： 1478-6419
年卷期： 2019 年 33 卷 8 期
页码：
收录情况： SCI
摘要： Four new gastrodin derivatives containing a trans-cinnamoyl unit (1-4) and nine known compounds (5-13) were isolated from the rhizomes of Gastrodia elata Blume. All these compounds were evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death, and compounds 7 and 12 showed potent activities with EC50 values of 10.5 and 10.2 mu M, respectively. [GRAPHICS] .
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