Negative-Pressure Cavitation Extraction of Secoisolariciresinol Diglycoside from Flaxseed Cakes
文献类型： 外文期刊
作者： Tian, Hao 1 ; Li, Wan-Yi 2 ; Xiao, Dan 2 ; Li, Zhi-Min 2 ; Wang, Jian-Wen 1 ;
作者机构： 1.Soochow Univ, Coll Pharmaceut Sci, Suzhou 215123, Peoples R China
2.Yunnan Acad Agr Sci, Inst Med Plants, Kunming 650205, Peoples R China
关键词： flaxseed cake;negative-pressure cavitation extraction;pilot-scale application;response surface methodology;secoisolariciresinol diglucoside
期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）
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收录情况： SCI
摘要： The negative-pressure cavitation extraction (NPCE) technique was applied firstly to extract secoisolariciresinol diglucoside (SDG) from flaxseed cakes. The significant extraction parameters were screened by fractional factorial design (FFD). The optimal parameters were determined using the central composite design (CCD) with the two variables, NaOH amount and the liquid/solid ratio. The conditions of the extraction were optimized by using response surface methodology (RSM). Under the optimal conditions, the extraction yield and the extraction purity of SDG was 16.25 mg/g and 3.86%, respectively. The efficiency of NPCE was compared with that of conventional extraction methods. Our results demonstrated that NPCE was comparable to the well-known ultrasound-assisted extraction in term of extraction yield and purity. This extraction technique has advantages of less time-consuming, low solvent usage and high throughput capability.
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