文献类型： 外文期刊
作者： Li, Wei 1 ; Shao, Ya-Ting 1 ; Yin, Tian-Peng 3 ; Yan, Hui 4 ; Shen, Bao-Chun 1 ; Li, Yuan-Yi 1 ; Xie, Hui-Ding 1 ; Sun, Z 1 ;
作者机构： 1.Kunming Med Univ, Sch Pharmaceut Sci, Kunming, Yunnan, Peoples R China
2.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming, Yunnan, Peoples R China
3.Zunyi Med Univ, Zhuhai Key Lab Fundamental & Appl Res Tradit Chin, Zhuhai Campus, Zhuhai, Peoples R China
4.Yunnan Acad Agr Sci, Inst Agr Environm & Resources, Kunming, Yunnan, Peoples R China
期刊名称：JOURNAL OF NATURAL PRODUCTS （ 影响因子：4.05； 五年影响因子：4.603 ）
ISSN： 0163-3864
年卷期： 2020 年 83 卷 11 期
页码：
收录情况： SCI
摘要： Penisarins A (1) and B (2), sesquiterpene coumarins with an unusual tricyclic sesquiterpene system, were isolated from endophytic Penicillium sp. KMU18029. Their structures were elucidated on the basis of spectroscopic methods, single-crystal X-ray diffraction, and electronic circular dichroism calculations. Compound 2 showed significant cytotoxicities against two human cancer cell lines, HL-60 and SMMC-7721, with IC50 values of 3.6 +/- 0.2 and 3.7 +/- 0.2 mu M, respectively.
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