Maillard Reaction Products with Anti-Tobacco Mosaic Virus Activities Generated in Processed Thermopsis lanceolata R. Br. Seed Extract
文献类型： 外文期刊
作者： Hu, Zhan-Xing 2 ; Zhang, Peng 2 ; Zou, Ji-Bin 2 ; An, Qiao 2 ; Yi, Ping 2 ; Yuan, Chun-Mao 2 ; Yang, Jue 2 ; Gu, Wei 2 ; Huang, Lie-Jun 2 ; Zhao, Li-Hua 1 ; Hao, Xiao-Jiang 2 ;
作者机构： 1.Yunnan Acad Agr Sci, Inst Biotechnol & Germplasm Resources, Kunming 650204, Peoples R China
2.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Peoples R China
3.Chinese Acad Sci, Guiyang 550002, Peoples R China
4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Chi, Kunming 650201, Peoples R China
5.Guizhou Univ Tradit Chinese Med, Guiyang 550025, Peoples R China
6.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Peoples R China
期刊名称：JOURNAL OF ORGANIC CHEMISTRY （ 影响因子：4.198； 五年影响因子：4.031 ）
ISSN： 0022-3263
年卷期： 2022 年 87 卷 17 期
页码：
收录情况： SCI
摘要： Six novel Maillard reaction products (MRPs) (1-6) were isolated from the processed Thermopsis lanceolata R. Br. seed extract, along with one biogenetically related intermediate (7). Compounds 1-4 possessed three rare dimerization patterns constructed by cytisine, whereas compounds 5 and 6 represented the first example of the addition products of cytisine and 5,6-dihydroxy-4-hexanolide. Their structures were elucidated by comprehensive spectroscopic data analysis and quantum chemistry calculations including GIAO C-13{H-1} NMR and ECD calculation, combined with single-crystal X-ray diffraction analysis. Biologically, compound 3 displayed significant anti-tobacco mosaic virus activity compared with the positive control ningnanmycin.
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