文献类型： 外文期刊
作者： Hu, Zhan-Xing 1 ; Zhao, Li-Hua 7 ; Tang, Hong-Yu 2 ; Aisa, Haji Aker 1 ; Zhang, Yu 2 ; Hao, Xiao-Jiang 2 ;
作者机构： 1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
3.Univ Chinese Acad Sci, Yuquan Rd 19, Beijing 100049, Peoples R China
4.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Guizhou, Peoples R China
5.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Guizhou, Peoples R China
6.Chinese Acad Sci, Guiyang 550002, Guizhou, Peoples R China
7.Yunnan Acad Agr Sci, Inst Biotechnol & Germplasm Resources, Kunming 650204, Yunnan, Peoples R China
8.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Yunnan, Peoples R China
关键词： Aconitwn apetalum; Anthranilamide derivatives; Anti-TMV
期刊名称：FITOTERAPIA （ 影响因子：2.882； 五年影响因子：3.202 ）
ISSN： 0367-326X
年卷期： 2018 年 128 卷
页码：
收录情况： SCI
摘要： Seven new anthranilamide derivatives, acoapetalines A-G (1-7), including one new naturally occurring compound (7), together with six known ones (8-13) were isolated from the whole plants of Aconitum apetalum. Their structures were established on the basis of extensive spectroscopic analyses (IR, UV, HRESIMS, 1D and 2D NMR). All compounds were evaluated for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compound 10 exhibited significant anti-TMV activity with an inhibition rate of 67.57% (100 mu g/mL), which was higher than that of ningnamycin (52.89%).
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