文献类型： 外文期刊
作者： Chen, Dao-Jun 1 ; Yuan, Shuang 1 ; Zhang, Peng 1 ; An, Qiao 1 ; Zou, Ji-Bin 1 ; Yuan, Chun-Mao 1 ; Zhao, Li-Hua 6 ; Hu, Zhan-Xing 1 ; Hao, Xiao-Jiang 1 ;
作者机构： 1.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Peoples R China
2.Guizhou Bailing Enterprise Grp Pharmaceut Co Ltd, Anshun 561000, Peoples R China
3.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Peoples R China
4.Chinese Acad Sci, Guiyang 550002, Peoples R China
5.Guizhou Univ Tradit Chinese Med, Sch Pharm, Guiyang 550025, Peoples R China
6.Yunnan Acad Agr Sci, Inst Biotechnol & Germplasm Resources, Kunming 650204, Yunnan, Peoples R China
7.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
关键词： Fabaceae; Sophora tonkinensis; isoflavone; anti-TMV; alpha-glucosidase inhibitory activity
期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.61； 五年影响因子：1.591 ）
ISSN： 1028-6020
年卷期：
页码：
收录情况： SCI
摘要： Two new isoflavones (1 and 2), as well as eight known ones were isolated from the roots of Sophora tonkinensis Gagnep. Compound 1 represents an unprecedented polymerization pattern constructed by isoflavone and cytisine. Their structures were elucidated by comprehensive spectroscopic data analysis, combined with ECD calculations. Compound 1 displayed significant anti-tobacco mosaic virus (TMV) activity compared with the positive control ningnanmycin. Moreover, compound 6 exhibited potent alpha-glucosidase inhibitory activity with IC50 value of 47.4 mg/L. [GRAPHICS] .
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