您好，欢迎访问云南省农业科学院 机构知识库！

Chiral molecularly imprinted polymeric stir bar sorptive extraction for naproxen enantiomer detection in PPCPs

文献类型： 外文期刊

作者： Liu, Yujian 1 ; Liu, Yuanchen 1 ; Liu, Zhimin 1 ; Zhao, Xingchen 2 ; Wei, Juntong 2 ; Liu, Hongcheng 3 ; Si, Xiaoxi 4 ; X 1 ;

作者机构： 1.Kunming Univ Sci & Technol, Fac Sci, Kunming 650500, Yunnan, Peoples R China

2.Hong Kong Baptist Univ, Dept Chem, State Key Lab Environm & Biol Anal, Hong Kong 999077, Peoples R China

3.Yunnan Acad Agr Sci, Inst Qual Standard & Testing Technol, Kunming 650223, Yunnan, Peoples R China

4.R&D Ctr China Tobacco Yunnan Ind Co Ltd, Kunming 650231, Yunnan, Peoples R China

关键词： Pharmaceuticals and personal care products; Chiral molecularly imprinted polymers; Heterochiral selectivity; Stir bar sorptive extraction; Naproxen; Enantiomers

期刊名称：JOURNAL OF HAZARDOUS MATERIALS （ 影响因子：10.588； 五年影响因子：10.129 ）

ISSN： 0304-3894

年卷期： 2020 年 392 卷

页码：

收录情况： SCI

摘要： Chiral micropollutant analysis in pharmaceuticals and personal care products (PPCPs) is interesting but challenging. We firstly developed a series of chiral molecularly imprinted polymeric (CMIP) stir bar sorptive extraction coatings by combining a chiral template with chiral functional monomers via a click reaction for naproxen enantiomer analysis in PPCP5. Heterochiral selectivity was observed in the molecule recognition of the CMIP coatings, which demonstrated good adsorption capability for the chiral template and its structurally similar chiral compounds. The coatings also exhibited excellent enrichment capability for chiral analyzes in an aqueous matrix. The surface morphology and pore structure of the CMIP coatings were characterized. The molecular interactions between the chiral template and chiral functional monomer were investigated through UV-vis spectroscopy and theoretical calculations to prove the effective interactions existing in the heterochiral MIPs. The CMIP coatings were used to enrich naproxen enantiomers in chiral drug and environmental water samples, and satisfactory recoveries (83.98 %-118.88 %) with a relative standard deviation of 3.49 %-13.08 % were achieved. The heterochiral imprinted coating-based method provided a sensitive, selective, and effective enrichment strategy for chiral micropollutant analysis in PPCPs. This technique is critical for chiral molecule recognition and enantiomer analysis in complex samples.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：云南省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台