文献类型： 外文期刊
作者： Pu, Xiao-Yun 1 ; Tian, Kai 1 ; Sun, Jing-Xian 1 ; Wang, Wei 1 ; Liu, Hong-Cheng 3 ; Yang, Juan 3 ; Jiang, Meng-Yuan 1 ; H 1 ;
作者机构： 1.Yunnan Minzu Univ, State Ethn Affairs Commiss, Key Lab Chem Ethn Med Resources, 2929 Yuehua St, Kunming 650504, Yunnan, Peoples R China
2.Yunnan Minzu Univ, Minist Educ, 2929 Yuehua St, Kunming 650504, Yunnan, Peoples R China
3.Yunnan Acad Agr Sci, Inst Qual Stand & Testing Technol, Kunming, Yunnan, Peoples R China
关键词： Monoterpene; Illigera aromatica; anti-inflammatory activity; hernandiaceae
期刊名称：NATURAL PRODUCT RESEARCH （ 影响因子：2.861； 五年影响因子：2.572 ）
ISSN： 1478-6419
年卷期：
页码：
收录情况： SCI
摘要： Two new monoterpene esters illigerates F and G (1 and 2) together with 5 know compounds illigerate A (3), illigerate C (4), actinodaphnine (5), N-methylactinodaphnine(6) and N-methyllaurotetanine(7) were isolated from Illigera aromatica S. Z. Huang et S. L. Mo. Their structures were identified by extensive NMR data and by comparing with the known compounds. The anti-inflammatory activity of four monoterpenes (1 - 4) was evaluated by inhibiting nitric oxide (NO) production in lipopolysaccharide-activated murine macrophage RAW 264.7 cells and four monoterpenoids exhibited inhibitory effect with IC50 values of 71.5 +/- 7.3, 74.7 +/- 5.6, 48.0 +/- 7.4 and 65.1 +/- 3.7 mu M, respectively. [GRAPHICS] .
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