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Ganodermasides E-H, four new ergosterol derivatives from the endophytic fungus Epicoccum poae DJ-F associated with Euphorbia royleana

文献类型： 外文期刊

作者： Chen, Ning 1 ; Chen, Shi-Wei 3 ; Qiu, Shi-Yu 3 ; Lu, Song-Mei 3 ; Wei, Ji-Rui 3 ; Yang, Fu-Wen 3 ; Geng, Hui-Chun 4 ; Zhou, Min 1 ;

作者机构： 1.Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Peoples R China

2.Yunnan Minzu Univ, Minist Educ, Kunming 650031, Peoples R China

3.Yunnan Minzu Univ, Sch Ethn Med, Kunming 650031, Peoples R China

4.Yunnan Acad Agr Sci, Inst Qual Stand & Testing Technol, Kunming 650223, Yunnan, Peoples R China

关键词： Epicoccum poae; Ergosterol derivative; Endophytic fungus; Antimicrobial activity

期刊名称：FITOTERAPIA （ 影响因子：3.4； 五年影响因子：3.3 ）

ISSN： 0367-326X

年卷期： 2023 年 168 卷

页码：

收录情况： SCI

摘要： Ganodermasides E-H (1-4), four new ergosterol derivatives and two known ones (5 and 6) were isolated from the fermentation of the endophytic fungus Epicoccum poae DJ-F in the stems of Euphorbia royleana Boiss. Their structures were elucidated by spectroscopic analysis, including extensive 1D NMR, 2D NMR, and HRESIMS techniques. All the isolated compounds were tested for their vitro antibacterial activity. Compounds 1-6 showed weak inhibitory effects on Staphylococcus epidermidis, Pseudomonas syringae, and Ralstonia solanacearum with MIC values ranging from 0.4 to 3.6 mM.

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