文献类型： 外文期刊
作者： Geng, Hui-Chun 1 ; Wang, Xue-Song 1 ; Liao, Yong-Jian 2 ; Qiu, Shi-Yu 2 ; Fang, Hai-Xian 1 ; Chen, Xing-Lian 1 ; Wang, Yun-Mei 1 ; Zhou, Min 2 ;
作者机构： 1.Yunnan Acad Agr Sci, Inst Qual Stand & Testing Technol, Kunming 650223, Yunnan, Peoples R China
2.Yunnan Minzu Univ, Sch Ethn Med, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss & Minist Educ, Kunming 650031, Peoples R China
关键词： Lepidium meyenii; Thiohydantoins; Racemic mixtures; Maca; Cytotoxicity
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.873； 五年影响因子：1.875 ）
ISSN： 1874-3900
年卷期： 2022 年 51 卷
页码：
收录情况： SCI
摘要： Three new thiohydantoins with a 2-thioxoimidazolidin-4-one nucleus, named macathiohydantoins P-R (1-3), along with one known analog (4), were isolated from the roots of Lepidium meyenii. Their structures were elucidated by means of analysis of extensive spectroscopic data, including D-1 NMR, D-2 NMR and HRESIMS. The thiohydantoins (1-4) were isolated as racemic mixtures, which were further separated by chiral semi-preparative HPLC to afford the corresponding enantiomers. Their absolute configuration of C-5 was assigned by comparison of optical rotation values with those reported in the literature. All thiohydantoin derivatives were evaluated for their cytotoxicities against five human cancer cell lines.
- 相关文献
作者其他论文 更多>>
-
Ganodermasides E-H, four new ergosterol derivatives from the endophytic fungus Epicoccum poae DJ-F associated with Euphorbia royleana
作者：Chen, Ning;Zhou, Min;Chen, Ning;Zhou, Min;Chen, Ning;Chen, Shi-Wei;Qiu, Shi-Yu;Lu, Song-Mei;Wei, Ji-Rui;Yang, Fu-Wen;Zhou, Min;Geng, Hui-Chun
关键词：Epicoccum poae; Ergosterol derivative; Endophytic fungus; Antimicrobial activity
-
Colletotrins A-C, three new sesquiterpenes from the endophytic fungus Colletotrichum iris strain S11
作者：Chen, Ning;Zhou, Min;Chen, Ning;Zhou, Min;Chen, Ning;Qiu, Shi-Yu;Lu, Song-Mei;Chen, Shi-Wei;Wei, Ji-Rui;Yang, Fu-Wen;Zhou, Min;Geng, Hui-Chun
关键词：Colletotrichum iris; Sesquiterpene; Cytotoxic activities; Euphorbia lathylris
-
Macathioureas A-D, four new thiourea analogues from the roots of Lepidium meyenii
作者：Geng, Hui-Chun;Chen, Ning;Lv, Jun-Jiang;Zhou, Min;Geng, Hui-Chun;Chen, Ning;Lv, Jun-Jiang;Zhou, Min;Geng, Hui-Chun;Wang, Xue-Song;Lv, Jun-Jiang
关键词：Lepidium meyenii; Thioureas; ECD; Cytotoxicity
-
Application of Time of Flight Mass Spectrometry in the Identification of Dendrobium devonianum Paxt and Dendrobium officinale Kimura et Migo Grown in Longling Area of Yunnan, China
作者：Lin, Tao;Chen, Xing-Lian;Sha, Ling-Jie;Liu, Hong-Cheng;Wang, Jing;Hu, Zheng-Xu;Wu, Guang-Wei;Cheng, Long
关键词：Time of flight mass spectrometry; identification; Dendrobium devonianum; Longling area
-
Simultaneous Determination and Health Risk Assessment of Four High Detection Rate Pesticide Residues in Pu'er Tea from Yunnan, China
作者：Lin, Tao;Chen, Xing-Lian;Li, Mao-Xuan;Li, Yan-Gang;Liu, Hong-Cheng;Lin, Tao;Chen, Xing-Lian;Li, Mao-Xuan;Li, Yan-Gang;Liu, Hong-Cheng;Guo, Jin;Li, Meng-Xia;Tang, Yu-Feng;Cheng, Long
关键词：high detection rate pesticides; multiwalled carbon nanotubes; risk assessment; Pu'er tea
-
Phyllanacidins A-C, three new cleistanthane diterpenoids from Phyllanthus acidus and their cytotoxicities
作者：Geng, Hui-Chun;Zhu, Hong-Tao;Wang, Dong;Yang, Chong-Ren;Zhang, Ying-Jun;Geng, Hui-Chun;Geng, Hui-Chun;Yang, Wei-Nong
关键词：Phyllanthus acidus; Cleistanthane diterpenoids; Cytotoxicity
-
Determination of Enantiomeric Excess by Solid-Phase Extraction Using a Chiral Metal-Organic Framework as Sorbent
作者：Zhang, Jun-Hui;Tang, Bo;Xie, Sheng-Ming;Wang, Bang-Jin;Zi, Min;Yuan, Li-Ming;Zhang, Mei;Chen, Xing-Lian
关键词：metal-organic frameworks; enantiomeric excess; chiral compounds; solid-phase extraction
