Phyllaciduloids E and F, two new cleistanthane diterpenoids from the leaves of Phyllanthus acidus
文献类型： 外文期刊
作者： Geng, Hui-Chun 1 ; Zhu, Hong-Tao 1 ; Yang, Wei-Nong 4 ; Wang, Dong 1 ; Yang, Chong-Ren 1 ; Zhang, Ying-Jun 1 ;
作者机构： 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Yunnan Acad Agr Sci, Qual Standardizing & Testing Technol Inst, Kunming, Yunnan, Peoples R China
4.Yunnan Xinxing Greening Engn Co, Kunming, Yunnan, Peoples R China
关键词： Phyllanthus acidus; cleistanthane diterpenoids; quantum chemical calculations; cytotoxicity
期刊名称：NATURAL PRODUCT RESEARCH （ 影响因子：2.862； 五年影响因子：2.572 ）
ISSN： 1478-6419
年卷期：
页码：
收录情况： SCI
摘要： Phyllaciduloids E (1) and F (2), two new cleistanthane diterpenoids, were isolated from the leaves of Phyllanthus acidus (L.) Skeels (Phyllanthaceae). Their planar structures were established by spectroscopic analysis and comparison with literature values. The relative configurations of phyllaciduloids E and F were confirmed by DFT-NMR chemical shift calculations and subsequent CP3 probability methods. Phyllaciduloids E and F were evaluated for their cytotoxicity. However, no significant activities were detected at concentrations up to 40 mu M.
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